Serial Femtosecond Crystallography User Consortium

The Serial Femtosecond Crystallography (SFX) user consortium will design, build, and commission an experimental instrument at the European XFEL for high-throughput structure determination of (nano)crystalline biological macromolecular samples. The femtosecond pulses overcome radiation damage and give the potential for measuring dynamics with high time resolution. The instrument utilises the spent beam from the Single Particles, Clusters, and Biomolecules (SPB) endstation, allowing two sets of experiments to be carried out simultaneously, with the same photon pulses. Together, theses stations form the innovative SPB/SFX beamline of the European XFEL.


The SFX user consortium is comprised of members of the scientific communities in Germany, United Kingdom, Sweden, Slovakia, Switzerland, United States and Australia.


The development and construction of the SFX focuses on the following research areas:

SFX Schematic Layout

Sample Injection System

Photon Detector


Data Acquisition